Restore Bio
Harnessing natural liver biology for in vivo Tregs & catalytic protein degradation
About Restore Bio
Restore Bio is developing therapeutics to address multiple disease factors common to complex autoimmune, allergy, and cardiovascular diseases. Our innovative liver-targeted platforms expand potent antigen/tissue-specific regulatory T cells in vivo to manage inflammatory responses and establish a durable catalytic pathway for deep, sustained protein degradation. Our groundbreaking technologies represent a new class of therapeutic solutions designed to address the root causes of disease as well as the acute drivers of pathology.
We are actively building a pipeline of novel therapeutics and seeking partnerships and collaborations to advance multiple products to the clinic.
Our Platform Technologies
In vivo regulatory T cell
Our proprietary platform addresses the root causes of disease by restoring immune tolerance and expanding a potent population of antigen/tissue-specific regulatory T cells. The platform enables precise immunomodulation without broad immunosuppression to treat autoimmune and allergy disorders.
Catalytic protein degradation
An innovative and durable catalytic protein degradation platform that selectively eliminates disease-causing proteins. offering a novel approach to treating cardiovascular, autoimmune, and allergy disorders.
Combination in vivo Treg & catalytic degradation
Precision antibody engineering combines the two platforms into a single biologic to treat both the root causes and acute drivers of disease.